Neetu Chandra was born in a middle class family in Patna, Bihar. She was an avid sportsperson. She is a black belt holder in Taekwondo. She has represented India in International Taekwondo Championship at Hong Kong in 1996 & World Korfball Championship in 1995 at New Delhi. She is a national games Silver Medal winner in Taekwondo. 

She received the Best Student Award for Sports & Academics given to her by the Prime Minister of India himself. Before plunging into the glamour world of Bollywood she undertook several modeling assignments & did various advertisements. Neetu even got opportunities to perform in a video for Abhijeet & for Bombay Vikings. 

Neetu got her debut role when director Priyadarshan selected her to play the role of an alluring airhostess in the comedy film Garam Masala opposite Akshay Kumar & John Abraham. Then she starred in the Telugu film Godavari in which she played the role of Rajeshwari. She appeared in the film Traffic Signal. She has also signed a Tamil-Malayalam bilingual starring Malayalam superstar Mohanlal & currently acting in the Tamil film, Yavarum Nalam with Madhavan. 

Besides doing several South Indian films Neetu will also act in Anupam Kher's home production called Homeland. Neetu was trained kathak dancer, practises Yoga &enjoys cooking. She is the life member of International Film and Television Club of Asian Academy of Film & Television. 

In the year 2008 she has four releases by Directors Dibakar Banerjee, Rahul Dholakia, Ashwini Dheer & Vikram. Neetu Chandra was playing lead character in a 3D mobile game. 7Seas Technologies announced that they will develop a 3D mobile game. The game titled on her name Neetu The Alien Killer.