Soha Ali Khan was born in New Delhi. She is daughter of Mansoor Ali Khan Pataudi the current nawab is a former captain of the Indian cricket team. Her mother Sharmila Tagore is a noted film actress & a distant relative of the Nobel laureate Rabindranath Tagore. Her brother, Saif Ali Khan is also a Bollywood actor.

She attended The British School in New Delhi then followed on to study History at Balliol College, Oxford University & has a Masters in International Relations from the London School of Economics and Political Sciences.

Soha worked for the Ford Foundation & Citibank. She is involved in a range of activities outside the acting world including serving on the Advisory Board for a new project of the public entrepreneur group, Res Publica. She has also recently modeled for the spring-summer collection of Globus, an Indian chain of boutiques.

Soha made her acting debut with the Bollywood production Dil Maange More where she shared credits with Shahid Kapoor & two other leading ladies.She has since received critical acclaim for her performances in the Bengali film Antar Mahal & Rang De Basanti. Her latest release was Khoya Khoya Chand.